Protein Purification
Cayman Chemical ThIordoxIn Rducts 1 InhIb 25mg
An irreversible inhibitor of TrxR1 (IC50 = 0.012 µM); inhibits TrxR1-induced reduction of Trx1 in a cell-free assay (IC50 = 4.3 µM); reduces the mitochondrial oxygen consumption rate in HCT116 cells at 10 µM; increases the intracellular levels of hydrogen peroxide in FaDu cancer cells in a time- and concentration-dependent manner; decreases the viability of FaDu cells (IC50 = 0.72 µM); decreases tumor growth in a FaDu HNSCC mouse xenograft model at 10 mg/kg twice per day; induces apoptosis in a FaDu HNSCC mouse xenograft model at 5 mg/kg daily; toxic to S. mansoni adult worms (LD50 = 10.07 µM)
Hampton Research SLICE PH REAGENT #22 (B10)
HR2-070-22/Slice pH #22 (B10), 185 ml - 1.0 M Succinic acid pH 5.7. Please note items from this supplier are non-returnable.
Hampton Research SLICE PH REAGENT #23 (B11)
HR2-070-23/Slice pH #23 (B11), 185 ml - 1.0 M Succinic acid pH 6.0. Please note items from this supplier are non-returnable.
Genscript Corporation LILRB4/CD85k/ILT3Biotin His
LILRB4 also known as CD85k and LIR-5 ILT3 is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains a 21 aa transmembrane segment and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM) LILRB4 is receptor for class I MHC antigens Recognizes a broad spectrum of HLA-A HLA-B HLA-C and HLA-G alleles
Genscript Corporation CEACAM-5/CD66e His Cynomolgu
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated
Medchemexpress LLC Boc-Pro-prolinal | 86925-97-5 | MFCD00890691 | 98.3% | 296.36 g/mol | C15H24N2O4 | 5 MG
Prolyl endopeptidase inhibitor 1 (Boc-Pro-prolinal) is a small-molecule inhibitor of prolyl endopeptidase (PEP) used in biochemical and pharmacological research. It displays high affinity (Ki = 15 nM) and has reported anti-amnesic effects in preclinical studies. The compound is supplied as a solid and as DMSO stock solutions, with recommended storage at -20°C for solid material and -80°C for long-term solvent stocks.
- High potency against prolyl endopeptidase (Ki = 15 nM).
- High purity (98.34%).
- Available as solid and as DMSO stock solutions.
- Supplied in research-scale quantities suitable for in vitro and preclinical studies.
- Storage instructions provided for solid and solvent formats.
Cayman Chemical ENPP1 InhIbItr 4e 5mg
An ENPP1 inhibitor (IC50 = 0.188 µM); inhibits ENPP1 in MDA-MB-231 cells (IC50 = 0.732 µM); selectively cytotoxic to 4T1 murine metastatic breast cancer cells (IC50 = 2.99 µM) over non-cancerous L-02 and 293T cells at 50 µM; increases serum levels of IFN-β in mice when administered at a dose of 0.5 mg/kg in combination with cGAMP
Cayman Chemical 2 3-O- 5-BromonthrnIloyl 3.5mg
Fluorescent ATP derivatives; inhibits mammalian AC1, AC2, and AC5 and B. pertussis AC toxin CyaA (Kis = 120, 450, 70, and 330 nM, respectively)
Genscript Corporation Benz-Neburase His
This enzyme can be used to remove all forms of DNA and RNA including double stranded single stranded linearized and circular forms
Genscript Corporation BCMA/TNFRSF17 His Avi Hum
B-cell maturation antigen (BCMA or BCM) also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is a protein that in humans is encoded by the TNFRSF17 gene TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF)